The Position

2024 Summer Intern - Genomic Technology

Department Summary

The Enzyme and Protein Engineering Department (EPE) is a dynamic hub of scientific innovation, divided into four distinct teams.

The Application and Sample Prep team, in which you will be positioned, specializes in developing workflows for sample preparation reagents prior to sequencing.

We also engage in early R&D for projects related to DNA methylation-specific workflows. The Polymerase Engineering team and the Pore Engineering Team focuses on the discovery, development, and characterization of novel polymerases, nano pores and associated proteins enabling the detection of single DNA molecules with unprecedented accuracy on our current system under development.

Finally, the Sequencing Analysis team with their expertise in data processing, analysis, and interpretation develops analytical tools to extract meaningful insights from sequencing data.

The EPE's teams work collaboratively to advance the development of our innovative sequencing technology.

This internship position is located in Santa Clara,on site

Key Responsibilities

To assist with Nanopore SBX project activities, sequencing Methylated DNA research, and other DNA sample preparation and application experiments.

Research, devise and characterize novel workflows for library preparation and target enrichment for sequencing of methylated templates

Perform hands-on assay development, NGS library preparation, target enrichment, and analysis

Integrate sample processing workflows on custom configured automation platforms

Characterize assays on the Nanopore sequencing platformOptimize workflows and reaction conditions for sample preparation protocols, to meet Sequencing By Xpandomer assay and system performance specifications

Program Highlights :

Intensive 12-weeks full time (40 hours per week) paid internship

Program start dates are in May / June (Summer)

A stipend, based on location, will be provided to help alleviate costs associated with the internship.

Ownership of challenging and impactful business-critical projects

Work with some of the most talented people in the biotechnology industry.

Who You Are (Required)

Must be pursuing a Master's Degree

Must have attained a Master's Degree

Must be pursuing a PhD

Must have attained a PhD

Required majors :

Molecular biology, Biology, Cellular biology, Biochemistry or Bioengineering

Required skills :

Laboratory molecular biology techniques; DNA gel analysis, western and southern blots, PCR, qPCR, familiarity with DNA methylation specific workflows.

Next Gen Nanopore sequencing and data analysis

Library preparation and Target enrichment techniques- Optimization of molecular biology reactions, including nucleic acid isolation, quantitation, fragmentation, purification, size enrichment, ligation, hybridization, and gene panel target enrichment

Experimental troubleshooting.

Other Preferred Qualifications

Excellent communication, collaboration, and interpersonal skills, Working in a fast pace Biotech environment

Experimental and data presentation for commercial biotech environment

DNA data analysis, computer databases, statistical software (JMP, Matlab), or computer programming languages (Python, R.)

Complements our culture and the standards that guide our daily behavior & decisions : Integrity, Courage, and Passion.

Relocation benefits are not available for this job posting.

Roche-R&D-Interns-2024

This position also qualifies for paid holiday time off benefits.

Last updated : 2024-10-19

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